Every competitive match Wycombe Wanderers played in 1980–81, in Isth P — 1 matches, 0 won, 0 drawn, 1 lost, with scorers and attendances where the record holds them.
| Date | Competition | Venue | Opponent | Their season | Score | Scorers | Att |
|---|---|---|---|---|---|---|---|
| 22 Nov 1980 | FA Cup | H | AFC Bournemouth | AFC Bournemouth 1980–81 | 0–3 |
All 60 Wycombe Wanderers seasons · Wycombe Wanderers head-to-head records · Wycombe Wanderers players