Chelsea have played Real Betis 5 times in competitive football, winning 4, drawing 0 and losing 1, first meeting on 5 Mar 1998 and most recently on 28 May 2025. Every meeting is listed below.
| Date | Season | Competition | Venue | Opponent | Score | Scorers | Att |
|---|---|---|---|---|---|---|---|
| 5 Mar 1998 | 1997–98 | Cup Winners' Cup | A | Real Betis | 2–1 | Tore André Flo, Tore André Flo | 31,000 |
| 19 Mar 1998 | 1997–98 | Cup Winners' Cup | H | Real Betis | 3–1 | Frank Sinclair, Di Matteo, Gianfranco Zola | 32,300 |
| 19 Oct 2005 | 2005–06 | Champions League | H | Real Betis | 4–0 | Didier Drogba 24, Ricardo Carvalho 44, Joe Cole 59, Hernan Crespo 64 | 36,450 |
| 1 Nov 2005 | 2005–06 | Champions League | A | Real Betis | 0–1 | 55,000 | |
| 28 May 2025 | 2024–25 | UEFA Conference League | A | Real Betis | 4–1 | Enzo Fernández 65, Nicolas Jackson 70, Jadon Sancho 83, Moisés Caicedo 90+1 | 39,754 |